Discover BHQnova Probes

Improved qPCR assays for copy number variation using double-quenched BHQ Probes

Excerpt 1  -- In this study, we designed a BHQnova™ Probe to CYP2D6, a common human CNV target, using LGC Biosearch Technologies’ RealTimeDesign™ software. This region of the human genome is known to harbor sequence rearrangements with clinical significance, through variation in gene copy number. Similarly, we apply BHQnova Probes for analysis of wheat samples that contain copy number variations that influence crop characteristics. The results reveal accurate quantification, but also the performance advantages of double-quenched probes.

Improved signal-to-noise values in CYP2D6 assay

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Visualise spectra to optimise multiplexing assays